Chapter 8 Flashcards

In the hippocampus, the enhancement of a weakly activated group of synapses when a nearby group is strongly activated.
long-term depression (LTD)
A persistent weakening of synapses based on recent patterns of activity.
long-term potentiation (LTP)
A persistent strengthening of synapses based on recent patterns of activity.
post-tetanic potentiation (PTP)
An enhancement of synaptic transmission resulting from high-frequency trains of action potentials.
Increased sensitivity to stimuli in an area surrounding an injury. Also, a generalized aversive response to an otherwise benign stimulus when it is paired with a noxious stimulus.
spike timing-dependent plasticity (STDP)
Timing-dependent activity, probably the result of Ca2+ signaling in the postsynaptic cell, that is required for the establishment of some forms of synaptic plasticity.
synaptic depression
A short-term decrease in synaptic strength resulting from the depletion of synaptic vesicles at active synapses.
synaptic facilitation
A rapid increase in synaptic strength that occurs when two or more action potentials invade the presynaptic terminal within a few milliseconds of each other.