Chapter 10 Flashcards

affective–motivational aspects of pain
The fear, anxiety, and autonomic nervous activation that accompany exposure to a noxious stimulus.
allodynia
The induction of pain by a normally innocuous stimulus.
anterolateral pathway
Ascending sensory pathway in the spinal cord and brainstem that carries information about pain and temperature to the thalamus.
endocannabinoids
A family of endogenous signals that participate in several forms of synaptic transmission, interacting cannabinoid receptors. These receptors are the molecular targets of the psychoactive component of the marijuana plant, Cannabis.
endogenous opioids
Peptide neuritransmitters in the central nervous system that have the same pharmacological effects as morphine and other derivatives of opium, being agonists at opioid receptors, virtually all of which contain the sequence Tyr-Gly-Gly-Phe. There are three classes: dynorphins, endorphins, and enkephalins.
hyperalgesia
Increased perception of pain.
neuropathic pain
Any chronic pain caused by damage to the central or peripheral nervous system.
nociceptors
Cutaneous and subcutaneous receptors (especially free nerve endings) specialized for the detection of harmful (noxious) stimuli.
placebo
An inert substance that when administered may, because of the circumstances, have physiological effects (a "placebo effect").
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